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|Title:||Chia (Salvia hispanica) harvest residue induces cytokine expression in rabbits|
|Author:||MONICA ILSY JIMENEZ ROJAS|
|Abstract:||The seed of chia plant (Salvia hispanica) is characterized by a high content of polyunsaturated fatty acids, which is an important source of -linolenic acid for human and animal consumption. During the harvest of the seed, waste is generated that contains remnants of leaves, stems and some seeds, which is generally discarded. The objective of the present work was to evaluate the e ect of chia seed residue (CSR) on protein expression of the rabbit immune system, when added as a supplement in the diets of animals deliberately induced to an intestinal infection. Twenty rabbits (New Zealand California) were randomly distributed in ve treatments and fed ve diets with di erent percentages of CSR inclusion (0, 10, 20, 30 and 40%). Quanti cation of the relative expression of the anti-in ammatory Interleukin-10 (IL-10) and Tumor Necrosis Factor (TNF- ) genes showed that as CSR inclusion levels increased up to 40%, mRNA expression of IL-10 increased signi cantly (22.4-fold) with respect to the control, while TNF- mRNA expression was inversely proportional, where a signi cant increase (7.47-fold) in mRNA expression was found in the control group. It is concluded that the indirect inclusion of -linolenic acid through the consumption of CSR induces a positive response in the immune system of the rabbits and represents an alternative for the formulation of rations with nutraceutical efffects.|
|Appears in Collections:||Vol. 5, Núm. 13 (2018)|
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